Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 18/20 | 0.49 |
| ▸ | VEGFA | P15692 | 6/20 | 0.48 |
| ▸ | ARNT | P27540 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18078538 | 1.00 | EPAS1 (0.49) | EPAS1VEGFAARNT | |
| SCHEMBL21362881 | 0.88 | EPAS1 (0.40) | EPAS1VEGFA | |
| SCHEMBL21432437 | 0.85 | EPAS1 (0.33) | EPAS1VEGFA | |
| SCHEMBL18049076 | 0.78 | EPAS1 (0.58) | EPAS1VEGFA | |
| SCHEMBL19858577 | 0.78 | EPAS1 (0.58) | EPAS1VEGFA | |
| SCHEMBL18048410 | 0.76 | EPAS1 (0.53) | EPAS1VEGFAARNT | |
| SCHEMBL18078463 | 0.76 | EPAS1 (0.53) | EPAS1VEGFAARNT | |
| SCHEMBL21362868 | 0.70 | EPAS1 (0.53) | EPAS1VEGFA | |
| SCHEMBL18689871 | 0.69 | SLC6A2 (0.36) | EPAS1 | |
| SCHEMBL28637879 | 0.67 | EPAS1 (0.61) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144825-A1 | AROMATIC COMPOUNDS AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | WO | disclosed |