Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arecoline SCHEMBL44065 | 0.78 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL640797 | 0.78 | CHRM2 (0.54) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Arecoline SCHEMBL527735 | 0.76 | BLM (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Arecoline SCHEMBL3057863 | 0.76 | CHRM2 (0.96) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9581487 | 0.76 | CHRM3 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9594622 | 0.71 | CHRM2 (0.56) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12043327 | 0.71 | CHRM2 (0.56) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL5203140 | 0.71 | CHRM2 (0.65) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL336164 | 0.71 | CHRM2 (0.65) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9568926 | 0.71 | CHRM2 (0.65) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265466-A1 | PERIPHERAL-ANTICHOLINERGIC MUSCARINIC AGONIST COMBINATION | Chase Pharmaceuticals Corporation (US) | 2018-01-10 | — | — | EP | claimed |
| WO-2016144727-A1 | PERIPHERAL-ANTICHOLINERGIC MUSCARINIC AGONIST COMBINATION | CHASE PHARMACEUTICALS CORPORATION (US) | 2016-09-15 | — | — | WO | claimed |