SCHEMBL18050854

SCHEMBL18050854

CCOC(=O)C(C)C(C)OC(=O)N(CC)CC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 5/20 0.33
LMNA P02545 3/20 0.33
HSD17B10 Q99714 2/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
SOAT1 P35610 1/20 0.31
POLB P06746 2/20 0.31
TP53 P04637 2/20 0.31
TSHR P16473 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18050823 0.86 MEN1 (0.34) MEN1KMT2AALDH1A1LMNA
SCHEMBL18050772 0.83 ALDH1A1 (0.40) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL18050842 0.82 ALDH1A1 (0.40) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL18050845 0.82 MEN1 (0.34) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL17092988 0.82 KMT2A (0.45) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL6893830 0.78 KMT2A (0.42) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL7744359 0.76 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL18050499 0.76 ALDH1A1 (0.50) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL6893989 0.74 KMT2A (0.42) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL8909949 0.73 KMT2A (0.45) MEN1KMT2AALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107278209-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2020-03-10 CN disclosed
EP-3268396-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-04-17 EP disclosed
US-10017590-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-07-10 US disclosed
US-20180057620-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-03-01 US disclosed
EP-3268396-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2018-01-17 EP disclosed
WO-2016142334-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2016-09-15 WO disclosed