SCHEMBL18050845

SCHEMBL18050845

CCOC(=O)C(C)C(CC)OC(=O)N(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
LMNA P02545 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18050854 0.82 MEN1 (0.36) MEN1KMT2ABCHEACHELMNA
SCHEMBL16964936 0.81 MEN1 (0.43) MEN1KMT2ABCHEACHELMNA
SCHEMBL18050517 0.78 ALDH1A1 (0.46) LMNAALDH1A1HSD17B10
SCHEMBL16965620 0.78 MEN1 (0.38) MEN1KMT2ALMNAALDH1A1HSD17B10
SCHEMBL16965126 0.75 MEN1 (0.36) MEN1KMT2AALDH1A1
SCHEMBL28366964 0.75 ABCB1 (0.36) MEN1KMT2ALMNA
SCHEMBL28627620 0.74 LMNA (0.40) MEN1KMT2ALMNAALDH1A1HSD17B10
SCHEMBL16965788 0.71 MEN1 (0.36) MEN1KMT2AALDH1A1
SCHEMBL9728294 0.71 KMT2A (0.42) MEN1KMT2ABCHEACHELMNA
SCHEMBL17092988 0.71 KMT2A (0.45) MEN1KMT2ABCHEACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107278209-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2020-03-10 CN disclosed
EP-3268396-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-04-17 EP disclosed
US-10017590-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-07-10 US disclosed
US-20180057620-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-03-01 US disclosed
EP-3268396-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2018-01-17 EP disclosed
WO-2016142334-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2016-09-15 WO disclosed