Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574827 | 0.86 | HDAC1 (0.37) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29353376 | 0.86 | HDAC1 (0.37) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18726574 | 0.86 | HDAC1 (0.37) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18656418 | 0.86 | HDAC1 (0.36) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL19188153 | 0.81 | HDAC1 (0.36) | HDAC1HDAC2ALDH1A1KMT2A | |
| SCHEMBL18896133 | 0.81 | HDAC1 (0.36) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18726765 | 0.81 | HDAC1 (0.40) | HDAC1HDAC2LMNAALDH1A1 | |
| SCHEMBL29427565 | 0.79 | HDAC1 (0.34) | HDAC1HDAC2 | |
| SCHEMBL17283454 | 0.78 | HDAC1 (0.43) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18651047 | 0.77 | KDM4E (0.35) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648510-B1 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS | IMMUNOGEN INC (US) | 2016-08-31 | — | — | EP | disclosed |