Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353376 | 0.90 | HDAC1 (0.37) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL574827 | 0.90 | HDAC1 (0.37) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18726574 | 0.90 | HDAC1 (0.37) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18726765 | 0.84 | HDAC1 (0.40) | HDAC1HDAC2LMNAALDH1A1EHMT2 | |
| SCHEMBL18656418 | 0.82 | HDAC1 (0.36) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18651047 | 0.81 | KDM4E (0.35) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18052247 | 0.81 | HDAC1 (0.37) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9904994 | 0.80 | HDAC1 (0.36) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL17283454 | 0.80 | HDAC1 (0.43) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL19188153 | 0.79 | HDAC1 (0.36) | HDAC1HDAC2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663492-B2 | Methods for the preparation of charged crosslinkers | IMMUNOGEN, INC. (US) | 2017-05-30 | — | — | US | disclosed |