SCHEMBL29353376

SCHEMBL29353376

O=C(ON1C(=O)CCC1=O)C(CCSSc1ccccn1)S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 13/20 0.37
HDAC2 Q92769 13/20 0.37
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
EHMT2 Q96KQ7 1/20 0.32
EHMT1 Q9H9B1 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18726574 1.00 HDAC1 (0.37) HDAC1HDAC2LMNAALDH1A1SMN1; SMN2
SCHEMBL574827 1.00 HDAC1 (0.37) HDAC1HDAC2LMNAALDH1A1SMN1; SMN2
SCHEMBL18726765 0.94 HDAC1 (0.40) HDAC1HDAC2LMNAALDH1A1EHMT2
SCHEMBL18896133 0.90 HDAC1 (0.36) HDAC1HDAC2LMNAALDH1A1SMN1; SMN2
SCHEMBL9904994 0.90 HDAC1 (0.36) HDAC1HDAC2LMNAALDH1A1SMN1; SMN2
SCHEMBL18656418 0.87 HDAC1 (0.36) HDAC1HDAC2LMNAALDH1A1SMN1; SMN2
SCHEMBL15994284 0.87 HPGD (0.38) HDAC1HDAC2LMNAALDH1A1MAPT
SCHEMBL18052247 0.86 HDAC1 (0.37) HDAC1HDAC2LMNAALDH1A1SMN1; SMN2
SCHEMBL29427565 0.86 HDAC1 (0.34) HDAC1HDAC2
SCHEMBL19188153 0.85 HDAC1 (0.36) HDAC1HDAC2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 981 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075735-A Therapeutic combinations comprising anti-FOLR 1 immunoconjugates 2026-05-26 CN claimed
CN-122028938-A Pharmaceutical combination comprising an anti-CD 37 antibody maytansinoid conjugate and a BCL2 inhibitor or PI3K inhibitor 德彪药业国际股份公司 2026-05-12 CN claimed
EP-4719483-A1 ANTITUMOR COMBINATIONS CONTAINING ANTI-CEACAM5 ANTIBODY-DRUG CONJUGATES, ANTI-PD1/PD-L1 ANTIBODIES AND ANTI-CTLA4 ANTIBODIES Sanofi (FR) 2026-04-08 EP claimed
EP-4713024-A1 CONJUGATE AND THE PREPARATION THEREOF Nanjing University (CN) 2026-03-25 EP claimed
US-12570761-B2 Anti-CEACAM5 antibodies and uses thereof SANOFI (FR) 2026-03-10 US claimed
US-20260061066-A1 ANTI-GRP78 ANTIBODY, IMMUNOCONJUGATE AND USES THEREOF UCT BIOSCIENCE CO., LTD. (TW) 2026-03-05 US claimed
EP-4688000-A1 ANTIBODY DRUG CONJUGATES CSTONE PHARMACEUTICALS (SUZHOU) CO., LTD. (CN) 2026-02-11 EP claimed
EP-4676541-A1 ANTITUMOR COMBINATIONS CONTAINING ANTI-CEACAM5 ANTIBODY-DRUG CONJUGATES, ANTI-VEGFR-2 ANTIBODIES AND ANTI-PD1/PD-L1 ANTIBODIES Sanofi (FR) 2026-01-14 EP claimed
EP-4673181-A1 USE OF ANTI-CEACAM5 IMMUNOCONJUGATES FOR TREATING NEUROENDOCRINE CANCERS EXPRESSING CEACAM5 Sanofi (FR) 2026-01-07 EP claimed
US-20250325717-A1 ANTI-NUCLEOPHOSMIN 1 ANTIBODY AND ANTIBODY CONJUGATE COMBINATION THERAPIES THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-10-23 US claimed
US-20220143208-A1 METHODS FOR INCREASING EFFICACY OF FOLR1 CANCER THERAPY IMMUNOGEN, INC. (US) 2022-05-12 US claimed
US-20220133899-A1 PREPARATION OF MAYTANSINOID ANTIBODY CONJUGATES BY A ONE-STEP PROCESS IMMUNOGEN INC. 2022-05-05 US claimed
US-11299515-B2 Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-12 US claimed
US-20220105198-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY IMMUNESENSOR THERAPEUTICS, INC. 2022-04-07 US claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN claimed
US-20220080053-A1 USE OF ANTI-CEACAM5 IMMUNOCONJUGATES FOR TREATING LUNG CANCER SANOFI (FR) 2022-03-17 US claimed
US-11274121-B2 Methods for antibody drug conjugation, purification, and formulation IMMUNOGEN, INC. (US) 2022-03-15 US claimed
CN-114173823-A Use of anti-CEACAM 5 immunoconjugates for treating lung cancer 赛诺菲 2022-03-11 CN claimed
EP-3962935-A1 BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES Immunogen, Inc. (US) 2022-03-09 EP claimed
WO-2022046941-A1 ANTIMITOTIC TETRAPEPTIDE-ANTIBODY CONJUGATES AND METHODS OF USING SAME ANGIEX, INC. (US) 2022-03-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570761-B2 Anti-CEACAM5 antibodies and uses thereof TNFRSF9, IGSF11, FCGR2A HDAC1 4725/4885HDAC2 4752/4885LMNA 2950/4885
US-20220105198-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY STING1, CGAS, MAVS HDAC1 4835/4885HDAC2 4695/4885LMNA 2981/4885
US-20220080053-A1 USE OF ANTI-CEACAM5 IMMUNOCONJUGATES FOR TREATING LUNG CANCER EPCAM, BSG, SIGLEC9 HDAC1 4029/4885HDAC2 3859/4885LMNA 3168/4885
US-20220133899-A1 PREPARATION OF MAYTANSINOID ANTIBODY CONJUGATES BY A ONE-STEP PROCESS CD47, CD22, CLSPN HDAC1 3862/4885HDAC2 4221/4885LMNA 2916/4885
US-20260061066-A1 ANTI-GRP78 ANTIBODY, IMMUNOCONJUGATE AND USES THEREOF IGSF11, DNAJC10, HSPA5 HDAC1 4660/4885HDAC2 4529/4885LMNA 4229/4885
US-11274121-B2 Methods for antibody drug conjugation, purification, and formulation FCGR2A, FCGR1A, FCGR3B HDAC1 4077/4885HDAC2 3412/4885LMNA 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.