SCHEMBL180559

SCHEMBL180559

N[C@H](CS(=O)(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
PMP22 Q01453 2/20 0.45
KYNU Q16719 2/20 0.44
NOS2 P35228 1/20 0.44
GCLC P48506 1/20 0.42
SLC1A1 P43005 4/20 0.42
SLC1A3 P43003 3/20 0.42
SLC1A2 P43004 3/20 0.42
GSR P00390 2/20 0.42
GRIK1 P39086 2/20 0.42
GRIK2 Q13002 2/20 0.42
GRM1 Q13255 2/20 0.42
GRM2 Q14416 2/20 0.42
SLC7A5 Q01650 1/20 0.42
GRM8 O00222 1/20 0.42
GRM6 O15303 1/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30600100 1.00 PTGS1 (0.46) PTGS1SLC7A11PMP22KYNUNOS2
SCHEMBL1395227 1.00 PTGS1 (0.46) PTGS1SLC7A11PMP22KYNUNOS2
SCHEMBL21518548 1.00 PTGS1 (0.46) PTGS1SLC7A11PMP22KYNUNOS2
SCHEMBL44030 1.00 PTGS1 (0.46) PTGS1SLC7A11PMP22KYNUNOS2
SCHEMBL44031 1.00 PTGS1 (0.46) PTGS1SLC7A11PMP22KYNUNOS2
SCHEMBL6570277 0.97 PTGS1 (0.44) PTGS1SLC7A11PMP22KYNUNOS2
SCHEMBL5046067 0.97 PTGS1 (0.44) PTGS1SLC7A11PMP22KYNUNOS2
Water SCHEMBL1157748 0.97 PTGS1 (0.44) PTGS1SLC7A11PMP22KYNUNOS2
SCHEMBL22720617 0.97 PTGS1 (0.44) PTGS1SLC7A11PMP22KYNUNOS2
SCHEMBL4872178 0.97 PTGS1 (0.44) PTGS1SLC7A11PMP22KYNUNOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12264146-B2 Rho kinase inhibitor, method for preparing same and uses thereof BEIJING INCREASE INNOVATIVE DRUG CO., LTD (CN) 2025-04-01 US claimed
EP-4464715-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 BicycleTx Limited (GB) 2024-11-20 EP claimed
EP-3359138-B1 DIETARY SUPPLEMENTATION TO ACHIEVE OXY-REDOX HOMEOSTASIS AND EPIGENETIC STABILITY PARTHENOGEN SAGL (CH) 2024-04-24 EP claimed
US-11898250-B2 Formulation for the etching of polymer materials prior to coating of the materials AVANZARE INNOVACIÓN TECNOLÓGICA, S.L. (ES) 2024-02-13 US claimed
US-20240000957-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 BICYCLETX LIMITED (GB) 2024-01-04 US claimed
US-11696956-B2 Bicyclic peptide ligands specific for EphA2 BICYCLETX LIMITED (GB) 2023-07-11 US claimed
EP-3917339-B1 AN ORAL NICOTINE PRODUCT COMPRISING A PH ADJUSTING AGENT SWEDISH MATCH NORTH EUROPE AB (SE) 2023-06-07 EP claimed
WO-2023007088-A1 FOOD SUPPLEMENT FOR COMBATING FEMALE AND MALE INFERTILITY NURIBIOL (FR) 2023-02-02 WO claimed
US-20220095671-A1 AN ORAL NICOTINE PRODUCT COMPRISING A PH ADJUSTING AGENT SWEDISH MATCH NORTH EUROPE AB (SE) 2022-03-31 US claimed
US-20220002265-A1 RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF BEIJING INCREASE INNOVATIVE DRUG CO., LTD (CN) 2022-01-06 US claimed
US-6733651-B1 Method for producing a cyanide-free solution of a gold compound that is suitable for galvanic gold baths W. C. HERAEUS GMBH & CO. KG (DE) 2004-05-11 US claimed
US-20030211172-A1 Composition and method for substantially reducing the deleterious effects of alcohol on the body JONES JEREMY PARK (US) 2003-11-13 US claimed
EP-1198623-B1 METHOD FOR PRODUCING A CYANIDE-FREE SOLUTION OF A GOLD COMPOUND THAT IS SUITABLE FOR GALVANIC GOLD BATHS HERAEUS GMBH W C (DE) 2003-03-19 EP claimed
WO-2002072048-A2 USE OF DIVALENT TROPOLONE SALTS FOR TREATMENT OF THE HAIR L'OREAL (FR) 2002-09-19 WO claimed
EP-0957890-B1 HAIR TREATMENT COMPOSITION CONTAINING METAL-AMINOACID COMPLEX UNILEVER PLC (GB) 2002-02-13 EP claimed
EP-0626166-B1 New process for permanent waving of hair and the composition therefor containing in association an amino or amidothiol and at least a mineral bromide OREAL (FR) 1997-03-19 EP claimed
US-5576326-A Copper amino acidate diimine nitrate compounds and their methyl derivatives and a process for preparing them UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (UNAM) (MX) 1996-11-19 US claimed
EP-0626166-A1 New process for permanent waving of hair and the composition therefore containing in association an amino or amidotial and at least a mineral bromide L'OREAL (FR) 1994-11-30 EP claimed
EP-0434445-A2 Process to obtain new mixed copper aminoacidate complexes from phenanthrolines and their alkyl derivatives to be used as anticancerigenic agents UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (MX) 1991-06-26 EP claimed
EP-0065395-B1 IMPROVED CHYMOPAPAIN AND METHOD FOR ITS PRODUCTION AND USE BOOTS-FLINT, INC. (a Delaware corp.) (US) 1988-08-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220002265-A1 RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF ROCK1, RHOA, ROCK2 PTGS1 34/4885SLC7A11 3959/4885PMP22 4534/4885
US-11696956-B2 Bicyclic peptide ligands specific for EphA2 EPHA2, EPHB2, ERBB2 PTGS1 3602/4885SLC7A11 2066/4885PMP22 2589/4885
US-20240000957-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 EPHA2, EPHB2, ERBB2 PTGS1 3602/4885SLC7A11 2066/4885PMP22 2589/4885
US-12264146-B2 Rho kinase inhibitor, method for preparing same and uses thereof ROCK1, RHOA, ROCK2 PTGS1 34/4885SLC7A11 3959/4885PMP22 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.