Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.44 |
| ▸ | GRIK1 known ✓ | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 known ✓ | Q13002 | 2/20 | 0.41 |
| ▸ | GRIA1 known ✓ | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 known ✓ | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 known ✓ | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 known ✓ | P48058 | 1/20 | 0.41 |
| ▸ | GRIN2A known ✓ | Q12879 | 1/20 | 0.41 |
| ▸ | GRIK3 known ✓ | Q13003 | 1/20 | 0.41 |
| ▸ | GRIK5 known ✓ | Q16478 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | KYNU | Q16719 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | GCLC | P48506 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1157749 | 1.00 | PTGS1 (0.44) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| Water SCHEMBL8816686 | 0.98 | PTGS1 (0.42) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| Water SCHEMBL8816682 | 0.98 | PTGS1 (0.42) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| SCHEMBL30600100 | 0.97 | PTGS1 (0.46) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| SCHEMBL44030 | 0.97 | PTGS1 (0.46) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| SCHEMBL180559 | 0.97 | PTGS1 (0.46) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| SCHEMBL44031 | 0.97 | PTGS1 (0.46) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| SCHEMBL1395227 | 0.97 | PTGS1 (0.46) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| SCHEMBL21518548 | 0.97 | PTGS1 (0.46) | PTGS1SLC7A11PMP22KYNUNOS2 | |
| SCHEMBL5046067 | 0.95 | PTGS1 (0.44) | PTGS1SLC7A11PMP22KYNUNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5757408-A | PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING | XEROX CORPORATION (US) | 1998-05-26 | — | — | US | claimed |
| US-5683793-A | Ink jet transparencies | XEROX CORPORATION (US) | 1997-11-04 | — | — | US | claimed |
| US-5589277-A | INK JET PRINTING, AQUEOUS INKS, FAST DRYING | XEROX CORPORATION (US) | 1996-12-31 | — | — | US | claimed |
| EP-0667246-A1 | Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds | XEROX CORPORATION (US) | 1995-08-16 | — | — | EP | claimed |
| EP-4188143-B1 | ARTICLES WITH ANTI-VIRAL PROPERTIES | FXI INC LTD (GB) | 2025-10-29 | — | — | EP | disclosed |
| US-20250017294-A1 | COATED SUBSTRATES AND ARTICLES WITH ANTI-VIRAL PROPERTIES, AND FABRICATION PROCESSES | FXI INC LTD (GB) | 2025-01-16 | — | — | US | disclosed |
| US-11930867-B2 | Coated substrates and articles with anti-viral properties, and fabrication processes | FXI INC. LIMITED (GB) | 2024-03-19 | — | — | US | disclosed |
| CN-116322909-A | Coated substrates and articles having antiviral properties | FXI有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-11678703-B2 | Coated substrates and articles with anti-viral properties, and fabrication processes | FXI INC. LIMITED (GB) | 2023-06-20 | — | — | US | disclosed |
| EP-4188143-A1 | COATED SUBSTRATES AND ARTICLES WITH ANTI-VIRAL PROPERTIES | FXI Inc. Limited (GB) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022024049-A1 | COATED SUBSTRATES AND ARTICLES WITH ANTI-VIRAL PROPERTIES | FXI INC. LIMITED (GB) | 2022-02-03 | — | — | WO | disclosed |
| US-20220030980-A1 | COATED SUBSTRATES AND ARTICLES WITH ANTI-VIRAL PROPERTIES, AND FABRICATION PROCESSES | FXI INC. LIMITED (GB) | 2022-02-03 | — | — | US | disclosed |
| US-20060281586-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-12-14 | — | — | US | disclosed |
| US-20060281587-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-12-14 | — | — | US | disclosed |
| US-20050245657-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-11-03 | — | — | US | disclosed |
| US-20050245652-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-11-03 | — | — | US | disclosed |
| EP-0142220-A1 | Cysteic acid and homocysteic acid analogues of methotrexate and aminopterin | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4490529-A | Cysteic acid and homocysteic acid analogues of methotrexate and aminopterin | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1984-12-25 | — | — | US | disclosed |
| US-4302593-A | RECOVERING THE AMINO ACID FROM THE COMPOUND AS A MEANS OF SEPARATION OR PURIFICATION FROM SOLUTION | LOWE ORVILLE G | 1981-11-24 | — | — | US | disclosed |
| US-3948922-A | USING SULFOXIDES, HALOGEN OR HYDROGEN HALIDE CATALYST | LOWE ORVILLE G | 1976-04-06 | — | — | US | disclosed |