Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126312 | 0.86 | CTSL (0.62) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL15722175 | 0.86 | CTSL (0.62) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL9728200 | 0.86 | CTSL (0.62) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL14532871 | 0.85 | CTSL (0.63) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL4407946 | 0.83 | CTSL (0.63) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL16190432 | 0.83 | CTSL (0.60) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL14532875 | 0.83 | CTSL (0.60) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL14534876 | 0.83 | CTSL (0.60) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL10063640 | 0.83 | CTSL (0.64) | CTSLHTR2AADRB1HTR1AADRA2A | |
| SCHEMBL739201 | 0.82 | HTR2A (0.66) | HTR2AADRB1HTR1AADRA2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058025-A1 | VAULTS ENGINEERED FOR HYDROPHOBIC DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-04-23 | — | — | WO | disclosed |
| US-8674972-B2 | Semiconductor device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120056861-A1 | SEMICONDUCTOR DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-03-08 | — | — | US | disclosed |