Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 7/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173063 | 0.88 | PYGB (0.97) | PYGBGAACA1CA2CA9 | |
| SCHEMBL4184772 | 0.88 | PYGB (0.97) | PYGBGAACA1CA2CA9 | |
| SCHEMBL4173060 | 0.87 | PYGB (1.00) | PYGBGAACA1CA2CA9 | |
| SCHEMBL4182342 | 0.87 | PYGB (1.00) | PYGBGAACA1CA2CA9 | |
| SCHEMBL17948329 | 0.86 | PYGB (0.58) | PYGBGAACA1CA2CA9 | |
| SCHEMBL13308253 | 0.80 | PYGB (0.70) | PYGBGAACA1CA2CA9 | |
| SCHEMBL15975750 | 0.78 | PYGB (0.67) | PYGBGAACA1CA2CA9 | |
| SCHEMBL24468938 | 0.77 | PYGB (0.62) | PYGBGAACA1CA2CA9 | |
| SCHEMBL18365283 | 0.77 | PYGB (0.62) | PYGBGAACA1CA2CA9 | |
| SCHEMBL18193284 | 0.75 | PYGB (0.64) | PYGBGAACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160257983-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | ISIS INNOVATION LIMITED (GB) | 2016-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257983-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | PTMS, PGLS, PSPH | PYGB 123/4885GAA 984/4885CA1 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.