SCHEMBL18059368

SCHEMBL18059368

NC1=CC[C@@H](Oc2ccccc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.35
SLC6A3 Q01959 3/20 0.35
HRH1 P35367 1/20 0.34
SLC6A4 P31645 2/20 0.33
MAOA P21397 1/20 0.31
SOS1 Q07889 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18727509 1.00 SLC6A2 (0.35) SLC6A2SLC6A3HRH1SLC6A4MAOA
SCHEMBL12153476 0.83 TEAD4 (0.36) CA1CA2CA9
SCHEMBL18726466 0.79 HRH1 (0.34) SLC6A2SLC6A3HRH1SLC6A4
SCHEMBL14401546 0.79 HRH1 (0.34) SLC6A2SLC6A3HRH1SLC6A4
SCHEMBL12153542 0.78 SLC6A2 (0.45) SLC6A2SLC6A3SLC6A4
SCHEMBL12296378 0.77 LTA4H (0.37) SLC6A2SLC6A3HRH1SLC6A4MAOA
SCHEMBL14326985 0.76 HRH1 (0.35) SLC6A2SLC6A3HRH1MAOA
SCHEMBL20762465 0.73 MAPT (0.45) MAOA
SCHEMBL10546701 0.69 SLC6A2 (0.47) SLC6A2SLC6A3HRH1SLC6A4
SCHEMBL7805579 0.69 HRH1 (0.45) SLC6A2SLC6A3HRH1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160257067-A1 Methods for Solid Freeform Fabrication RICOH CO., LTD. (JP) 2016-09-08 US disclosed
EP-3064526-A1 METHODS FOR SOLID FREEFORM FABRICATION Ricoh Company, Ltd. (JP) 2016-09-07 EP disclosed