Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546701 | 0.79 | SLC6A2 (0.47) | HRH1SLC6A2SLC6A3SLC6A4LTA4H | |
| SCHEMBL17054596 | 0.74 | SLC6A2 (0.36) | HRH1SLC6A2SLC6A3SLC6A4TDP1 | |
| SCHEMBL1930886 | 0.73 | HRH1 (0.41) | HRH1SLC6A2SLC6A3SLC6A4LTA4H | |
| SCHEMBL3345179 | 0.73 | HRH1 (0.37) | HRH1SLC6A2SLC6A3SLC6A4LTA4H | |
| SCHEMBL10806280 | 0.73 | HRH1 (0.41) | HRH1SLC6A2SLC6A3SLC6A4LTA4H | |
| SCHEMBL29856 | 0.70 | HRH1 (0.71) | HRH1SLC6A2SLC6A3SLC6A4LTA4H | |
| SCHEMBL10339339 | 0.70 | HRH1 (0.42) | HRH1SLC6A2SLC6A3SLC6A4LTA4H | |
| SCHEMBL8516527 | 0.70 | HRH1 (0.42) | HRH1SLC6A2SLC6A3SLC6A4LTA4H | |
| SCHEMBL18656144 | 0.69 | SLC6A2 (0.36) | HRH1SLC6A2SLC6A3SLC6A4CA4 | |
| SCHEMBL18727509 | 0.69 | SLC6A2 (0.35) | HRH1SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |