Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CALML3 | P27482 | 1/20 | 0.40 |
| ▸ | SDHA | P31040 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480376 | 1.00 | MAOA (0.48) | MAOAMAOBGPR119LMNAPTGS1 | |
| SCHEMBL2450926 | 0.91 | MAOA (0.47) | MAOAMAOBGPR119LMNAPTGS1 | |
| SCHEMBL2507042 | 0.91 | MAOA (0.47) | MAOAMAOBGPR119LMNAPTGS1 | |
| SCHEMBL80077 | 0.89 | MAOB (0.58) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3396418 | 0.89 | MAOB (0.58) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL2452754 | 0.87 | MAOA (0.57) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7486020 | 0.87 | MAOA (0.57) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL2483101 | 0.86 | MAOA (0.43) | MAOAMAOBGPR119LMNAPTGS1 | |
| SCHEMBL2499941 | 0.86 | MAOA (0.43) | MAOAMAOBGPR119LMNAPTGS1 | |
| SCHEMBL2503390 | 0.86 | MAOB (0.47) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367820-B1 | NOVEL ANTIMICROBIAL AGENTS | PANACEA BIOTEC LTD (IN) | 2016-09-21 | — | — | EP | disclosed |