Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 1/20 | 1.00 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisomycin SCHEMBL8331774 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL2270183 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL2270193 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL59587 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL15033472 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL2270187 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL898674 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL1003579 | 0.99 | SMN1; SMN2 (0.97) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL6888777 | 0.94 | SMN1; SMN2 (0.89) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| SCHEMBL18106096 | 0.88 | CYP2D6 (0.78) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3069732-B1 | DRUG FOR TREATING CORNEAL ENDOTHELIUM BY PROMOTING CELL PROLIFERATION OR INHIBITING CELL DAMAGE | THE DOSHISHA (JP) | 2023-07-12 | — | — | EP | disclosed |
| US-10813920-B2 | Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage | THE DOSHISHA (JP) | 2020-10-27 | — | — | US | disclosed |
| US-20160331736-A1 | DRUG FOR TREATING CORNEAL ENDOTHELIUM BY PROMOTING CELL PROLIFERATION OR INHIBITING CELL DAMAGE | THE DOSHISHA (JP) | 2016-11-17 | — | — | US | disclosed |
| EP-3069732-A1 | DRUG FOR TREATING CORNEAL ENDOTHELIUM BY PROMOTING CELL PROLIFERATION OR INHIBITING CELL DAMAGE | The Doshisha (JP) | 2016-09-21 | — | — | EP | disclosed |