Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Anisomycin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.97 |
| ▸ | LMNA | P02545 | 1/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.97 |
| ▸ | MEN1 | O00255 | 1/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.97 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.97 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisomycin SCHEMBL2270193 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL2270187 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL2270183 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL59587 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL15033472 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL18059879 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL898674 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL8331774 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Anisomycin SCHEMBL6888777 | 0.93 | SMN1; SMN2 (0.89) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL30860185 | 0.88 | SMN1; SMN2 (0.76) | SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120091810-A | Methods and highly bioavailable permeable compounds for treating viral diseases | 基里尔·迪丹克 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024103178-A1 | ANISOMYCIN ANALOGS AND USES THEREOF | Université de Montréal (CA) | 2024-05-23 | — | — | WO | disclosed |
| US-10743604-B2 | Articles of manufacture releasing an active ingredient | NNTT TECH INC. (CA) | 2020-08-18 | — | — | US | disclosed |
| EP-3434264-A1 | MICROPARTICLE FOR RELEASING AN ACITVE AGENT | Biomod Concepts Inc. (CA) | 2019-01-30 | — | — | EP | disclosed |
| EP-2317984-B1 | ARTICLES OF MANUFACTURE RELEASING AN ACTIVE INGREDIENT | BIOMOD CONCEPTS INC (CA) | 2018-10-31 | — | — | EP | disclosed |
| US-20180146735-A1 | Articles Of Manufacture Releasing An Active Ingredient | NNTT TECH INC. (CA) | 2018-05-31 | — | — | US | disclosed |
| US-9883710-B2 | Articles of manufacture releasing an active ingredient | BIOMOD CONCEPTS INC. (CA) | 2018-02-06 | — | — | US | disclosed |
| US-9861154-B2 | Articles of manufacture releasing an active ingredient | BIOMOD COLLECTION INC. (CA) | 2018-01-09 | — | — | US | disclosed |
| US-9730483-B2 | Articles of manufacture releasing an active ingredient | BIOMOD CONCEPTS INC. (CA) | 2017-08-15 | — | — | US | disclosed |
| EP-2317984-A1 | ARTICLES OF MANUFACTURE RELEASING AN ACTIVE INGREDIENT | Biomod Concepts Inc. (CA) | 2011-05-11 | — | — | EP | disclosed |
| US-6391453-B1 | BINDER IS APPLIED TO PARTICLES WHICH ARE THEN COMBINED WITH FIBERS TO BIND THE PARTICLES TO THE FIBERS; THE THREE COMPONENTS ARE CAPABLE OF HYDROGEN BONDING AND/OR COORDINATE COVALENT BONDING TO EACH OTHER; FIBERS ARE EASILY DENSIFIED | WEYERNAEUSER COMPANY | 2002-05-21 | — | — | US | disclosed |
| US-6340411-B1 | Fibrous product containing densifying agent | WEYERHAEUSER COMPANY | 2002-01-22 | — | — | US | disclosed |
| EP-0745160-A1 | DENSIFYING AGENTS FOR ENHANCING FIBER DENSIFICATION | WEYERHAEUSER COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |
| WO-1995022655-A1 | DENSIFYING AGENTS FOR ENHANCING FIBER DENSIFICATION | WEYERHAEUSER COMPANY (US) | 1995-08-24 | — | — | WO | disclosed |
| EP-0655971-A4 | PARTICLE BINDERS. | WEYERHAEUSER CO (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0655970-A4 | PARTICLE BINDING TO FIBERS. | WEYERHAEUSER CO (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0655971-A1 | PARTICLE BINDERS | WEYERHAEUSER COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0655970-A1 | PARTICLE BINDING TO FIBERS | WEYERHAEUSER COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994004352-A1 | PARTICLE BINDERS | WEYERHAEUSER COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1994004351-A1 | PARTICLE BINDING TO FIBERS | WEYERHAEUSER COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |