Anisomycin

Anisomycin

SCHEMBL2270183

COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 5/20 1.00
▸ CYP2D6 P10635 3/20 1.00
▸ ALDH1A1 P00352 2/20 1.00
▸ LMNA P02545 1/20 1.00
▸ MAPK1 P28482 1/20 1.00
▸ HIF1A Q16665 1/20 1.00
▸ MEN1 O00255 1/20 1.00
▸ CYP2C9 P11712 1/20 1.00
▸ CYP2C19 P33261 1/20 1.00
▸ KMT2A Q03164 1/20 1.00
▸ SLC2A1 P11166 1/20 1.00
▸ GBA1 P04062 2/20 0.39
▸ GLA P06280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisomycin SCHEMBL18059879 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
Anisomycin SCHEMBL8331774 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
Anisomycin SCHEMBL2270193 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
Anisomycin SCHEMBL59587 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
Anisomycin SCHEMBL15033472 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
Anisomycin SCHEMBL2270187 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
Anisomycin SCHEMBL898674 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
Anisomycin SCHEMBL1003579 0.99 SMN1; SMN2 (0.97) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
Anisomycin SCHEMBL6888777 0.94 SMN1; SMN2 (0.89) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1
SCHEMBL18106096 0.88 CYP2D6 (0.78) SMN1; SMN2CYP2D6ALDH1A1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 — — EP claimed
EP-3226883-B1 COMPOSITIONS FOR TREATMENT OF RETINAL DEGENERATIVE DISEASES MOR RESEARCH APPLIC LTD (IL) 2023-11-22 — — EP claimed
US-20220249504-A1 LONGEVITY SIGNATURES AND THEIR APPLICATIONS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2022-08-11 — — US claimed
EP-3319965-B1 NOVEL COMPOUNDS FOR USE IN TREATING OR PREVENTING CANCEROUS DISEASES BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS (GR) 2022-05-04 — — EP claimed
WO-2021007551-A1 LONGEVITY SIGNATURES AND THEIR APPLICATIONS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2021-01-14 — — WO claimed
WO-2026086871-A1 ANTI-AGEING COMPOUNDS, USES THEREFOR, METHOD FOR IDENTIFYING, AND COMPOSITIONS CONTAINING Centre for Translational Stem Cell Biology Limited (CN) 2026-04-30 — — WO disclosed
WO-2026086871-A1 ANTI-AGEING COMPOUNDS, USES THEREFOR, METHOD FOR IDENTIFYING, AND COMPOSITIONS CONTAINING Centre for Translational Stem Cell Biology Limited (CN) 2026-04-30 — — WO disclosed
WO-2026089015-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR LIVESTOCK INFECTIOUS DISEASE CAUSED BY AFRICAN SWINE FEVER VIRUS 国立研究開発法人農業・食品産業技術総合研究機構 2026-04-30 — — WO disclosed
US-12612362-B2 Anisomycin derivative and use of anisomycin and derivative thereof as GLP-1R agonist SHANXI MEDICAL UNIVERSITY (CN) 2026-04-28 — — US disclosed
EP-4709874-A1 MODULATORS OF PROTEIN SECRETION Sanofi (FR) 2026-03-18 — — EP disclosed
US-20250313905-A1 METHODS AND COMPOSITIONS FOR IMPROVED PSYCHOLOGICAL AND RESILIENCE MEASURES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-10-09 — — US disclosed
US-12364717-B2 Compositions and methods for inhibiting seizures THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-22 — — US disclosed
US-20110195929-A1 COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS SUMMIT CORPORATION PLC (GB) 2011-08-11 — — US disclosed
US-20110118136-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions KOESTER HUBERT 2011-05-19 — — US disclosed
US-20100298168-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions HK PHARMACEUTICALS, INC. 2010-11-25 — — US disclosed
US-20100248264-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions HK PHARMACEUTICALS, INC. 2010-09-30 — — US disclosed
US-7666849-B2 ligands that are designed to specifically kill or inhibit the growth of any target organism RIB-X PHARMACEUTICALS, INC. (US) 2010-02-23 — — US disclosed
EP-2053406-A2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions caprotec bioanalytics GmbH (DE) 2009-04-29 — — EP disclosed
EP-1485707-B1 CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS CAPROTEC BIOANALYTICS GMBH (DE) 2009-01-14 — — EP disclosed
WO-1999001150-A1 NOVEL COMPOSITION FOR TREATING, PREVENTING AND/OR DELAYING ISCHEMIC CELL DEATH MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1999-01-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118136-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions PTMS, QPCTL, SRMS SMN1; SMN2 4623/4885CYP2D6 4323/4885ALDH1A1 4360/4885
US-20110195929-A1 COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS GPI, GALE, HAVCR2 SMN1; SMN2 294/4885CYP2D6 630/4885ALDH1A1 1382/4885
US-12612362-B2 Anisomycin derivative and use of anisomycin and derivative thereof as GLP-1R agonist GLP1R, GIPR, GPR119 SMN1; SMN2 1606/4885CYP2D6 2161/4885ALDH1A1 1548/4885
US-20220249504-A1 LONGEVITY SIGNATURES AND THEIR APPLICATIONS GLA, LIMS1, GLB1 SMN1; SMN2 217/4885CYP2D6 4614/4885ALDH1A1 2370/4885
US-20100298168-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions CHLSN, PTMS, SRMS SMN1; SMN2 3130/4885CYP2D6 4202/4885ALDH1A1 4064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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