Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18060588 | 0.87 | CA2 (0.37) | PTGS1PTGS2CA1CA2GAA | |
| SCHEMBL18060590 | 0.82 | CA1 (0.36) | PTGS1PTGS2CA1CA2GAA | |
| SCHEMBL724696 | 0.81 | NR5A2 (0.39) | PTGS1PTGS2CA1CA2GAA | |
| SCHEMBL18060589 | 0.75 | PTGS2 (0.41) | PTGS1PTGS2CA1CA2GAA | |
| SCHEMBL10136751 | 0.74 | CA2 (0.40) | PTGS1PTGS2CA1CA2GAA | |
| SCHEMBL18060592 | 0.73 | PTGS1 (0.37) | PTGS1PTGS2CA1CA2KMT2A | |
| SCHEMBL10136766 | 0.72 | CA2 (0.43) | PTGS1PTGS2CA1CA2POLB | |
| SCHEMBL723478 | 0.72 | CA2 (0.40) | PTGS1PTGS2CA1CA2GAA | |
| SCHEMBL721937 | 0.68 | PTGS1 (0.40) | PTGS1PTGS2CA1CA2KMT2A | |
| SCHEMBL18060595 | 0.68 | CA2 (0.38) | PTGS1PTGS2CA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751084-B1 | PYRIMIDINE CARBOXAMIDE DERIVATIVES | EUDIS BIOTECH LLC (CN) | 2016-09-21 | — | — | EP | claimed |