SCHEMBL1806291

SCHEMBL1806291

NC(=O)c1cc(S(=O)(=O)O)ccc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
HSD17B10 Q99714 4/20 0.53
KDM4E B2RXH2 4/20 0.49
IKBKB O14920 1/20 0.49
HPGD P15428 1/20 0.49
PKM P14618 2/20 0.48
GAA P10253 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
CASP6 P55212 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TSHR P16473 2/20 0.47
NT5E P21589 2/20 0.47
TDP1 Q9NUW8 1/20 0.46
S1PR3 Q99500 1/20 0.40
HTR6 P50406 1/20 0.40
CA2 P00918 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30873374 1.00 ALDH1A1 (0.53) ALDH1A1HSD17B10KDM4EIKBKBHPGD
SCHEMBL342600 0.85 ALDH1A1 (0.62) ALDH1A1HSD17B10KDM4EHPGDPKM
SCHEMBL1805819 0.85 KDM4E (0.63) ALDH1A1HSD17B10KDM4EIKBKBHPGD
SCHEMBL1806762 0.85 ALDH1A1 (0.58) ALDH1A1HSD17B10KDM4EIKBKBHPGD
SCHEMBL6865738 0.84 ALDH1A1 (0.52) ALDH1A1HSD17B10KDM4EHPGDPKM
SCHEMBL11747783 0.83 ALDH1A1 (0.52) ALDH1A1HSD17B10KDM4EHPGDPKM
Ammonia Solution, Strong SCHEMBL7095002 0.82 ALDH1A1 (0.50) ALDH1A1HSD17B10KDM4EHPGDPKM
SCHEMBL5707621 0.81 ALDH1A1 (0.50) ALDH1A1HSD17B10KDM4EHPGDPKM
Ethane SCHEMBL27571371 0.81 ALDH1A1 (0.59) ALDH1A1HSD17B10KDM4EHPGDPKM
SCHEMBL391971 0.81 ALDH1A1 (0.69) ALDH1A1HSD17B10KDM4EHPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8834620-B2 Black disazo dyes, their preparation and use ILFORD IMAGING SWITZERLAND GMBH (CH) 2014-09-16 US disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20120090503-A1 BLACK DISAZO DYES, THEIR PREPARATION AND USE ILFORD IMAGING SWITZERLAND GMBH 2012-04-19 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 ALDH1A1 218/4885HSD17B10 2848/4885KDM4E 1406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.