Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939993 | 0.85 | ALDH1A1 (0.64) | KMT2AMAPK1ALDH1A1MAPTRAB9A | |
| SCHEMBL14928576 | 0.82 | ELANE (0.53) | KMT2AELANEALDH1A1MMP1MMP2 | |
| SCHEMBL10210078 | 0.82 | ELANE (0.53) | KMT2AELANEALDH1A1MMP1MMP2 | |
| SCHEMBL2875215 | 0.82 | KMT2A (0.59) | KMT2AMAPK1ALDH1A1MAPTRAB9A | |
| SCHEMBL22242662 | 0.82 | KMT2A (0.59) | KMT2AMAPK1ALDH1A1MAPTRAB9A | |
| SCHEMBL2875218 | 0.82 | KMT2A (0.59) | KMT2AMAPK1ALDH1A1MAPTRAB9A | |
| SCHEMBL17280822 | 0.82 | ALDH1A1 (0.64) | KMT2AMAPK1ELANEALDH1A1MAPT | |
| SCHEMBL3435525 | 0.82 | ALDH1A1 (0.64) | KMT2AMAPK1ELANEALDH1A1MAPT | |
| SCHEMBL6699242 | 0.82 | ALDH1A1 (0.64) | KMT2AMAPK1ELANEALDH1A1MAPT | |
| SCHEMBL17595505 | 0.82 | MAPK1 (0.59) | KMT2AMAPK1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770711-B2 | General catalyst for C-H functionalization | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-09-26 | — | — | US | disclosed |
| US-20160272662-A1 | GENERAL CATALYST FOR C-H FUNCTIONALIZATION | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272662-A1 | GENERAL CATALYST FOR C-H FUNCTIONALIZATION | BET1, PLEC, NUDC | KMT2A 3858/4885MAPK1 2303/4885ELANE 1815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.