Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 15/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14921353 | 0.87 | MAPK1 (0.67) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL14921954 | 0.86 | KEAP1 (0.66) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL19067070 | 0.86 | KEAP1 (0.57) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL14921403 | 0.85 | MAPK1 (0.65) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL16017668 | 0.84 | MAPK1 (0.67) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL14921401 | 0.83 | ALDH1A1 (1.00) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL14921399 | 0.83 | ALDH1A1 (1.00) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL23815775 | 0.83 | KEAP1 (1.00) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL14934022 | 0.83 | KEAP1 (1.00) | KEAP1NPSR1ALDH1A1NFE2L2ATM | |
| SCHEMBL20208400 | 0.83 | KEAP1 (1.00) | KEAP1NPSR1ALDH1A1NFE2L2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657017-B2 | Crystal form of (R)-praziquantel and preparation method and application thereof | TONGLI BIOMEDICAL CO., LTD. (CN) | 2017-05-23 | — | — | US | disclosed |
| US-20160272636-A1 | CRYSTAL FORM OF (R)-PRAZIQUANTEL AND PREPARATION METHOD AND APPLICATION THEREOF | TONGLI BIOMEDICAL CO., LTD (CN) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272636-A1 | CRYSTAL FORM OF (R)-PRAZIQUANTEL AND PREPARATION METHOD AND APPLICATION THEREOF | CYP2C9, CYP1A2, CYP4B1 | KEAP1 3285/4885NPSR1 2982/4885ALDH1A1 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.