Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804713 | 0.91 | NFKB1 (0.38) | EPHX1CHRM1L3MBTL1ALDH1A1POLB | |
| SCHEMBL1807692 | 0.91 | NFKB1 (0.38) | EPHX1CHRM1L3MBTL1ALDH1A1POLB | |
| SCHEMBL1559465 | 0.85 | NFKB1 (0.42) | EPHX1CHRM1L3MBTL1ALDH1A1POLB | |
| SCHEMBL7642227 | 0.82 | NFKB1 (0.41) | EPHX1CHRM1ALDH1A1GAARECQL | |
| SCHEMBL8396643 | 0.78 | EPHX1 (0.53) | EPHX1L3MBTL1GAAMAPTTHRB | |
| SCHEMBL1053459 | 0.78 | EPHX1 (0.57) | EPHX1L3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL12989351 | 0.78 | EPHX1 (0.43) | EPHX1GAAHPGD | |
| SCHEMBL20350198 | 0.77 | EPHX1 (0.60) | EPHX1L3MBTL1ALDH1A1MAPTTHRB | |
| SCHEMBL2802318 | 0.77 | EPHX1 (0.60) | EPHX1L3MBTL1ALDH1A1MAPTTHRB | |
| SCHEMBL8393517 | 0.77 | EPHX1 (0.60) | EPHX1L3MBTL1ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501961-B2 | HIV protease inhibitors and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2013-08-06 | — | — | US | disclosed |
| US-20110118330-A1 | HIV PROTEASE INHIBITORS AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118330-A1 | HIV PROTEASE INHIBITORS AND METHODS FOR USING | SERPINB1, PREP, PEPD | EPHX1 948/4885CHRM1 4827/4885L3MBTL1 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.