Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12076045 | 0.99 | ALDH1A1 (0.44) | ALDH1A1LMNARBP4KLKB1CYP19A1 | |
| SCHEMBL12080676 | 0.99 | ALDH1A1 (0.44) | ALDH1A1LMNARBP4KLKB1CYP19A1 | |
| SCHEMBL12076047 | 0.99 | ALDH1A1 (0.44) | ALDH1A1LMNARBP4KLKB1CYP19A1 | |
| Lithium Ion SCHEMBL31309892 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNARBP4KLKB1CYP19A1 | |
| SCHEMBL18353717 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNARBP4KLKB1CYP19A1 | |
| SCHEMBL20656320 | 0.81 | KLKB1 (0.44) | ALDH1A1LMNARBP4KLKB1CYP19A1 | |
| SCHEMBL9248509 | 0.80 | LMNA (0.60) | ALDH1A1LMNARBP4KLKB1CYP19A1 | |
| SCHEMBL16921555 | 0.77 | GRM2 (0.45) | RBP4KLKB1CDK5CDK5R1KDM5A | |
| SCHEMBL1129548 | 0.76 | KLKB1 (0.47) | ALDH1A1LMNARBP4KLKB1CDK5 | |
| SCHEMBL12282753 | 0.74 | MAPT (0.47) | ALDH1A1LMNAMAPK1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051540-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORPORATION (FI) | 2011-05-05 | — | — | WO | disclosed |