SCHEMBL1807019

SCHEMBL1807019

Cc1cc(N)ccc1S(N)(=O)=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.70
ALDH1A1 P00352 5/20 0.56
KDM4E B2RXH2 3/20 0.56
CYP3A4 P08684 2/20 0.56
MEN1 O00255 2/20 0.56
MAPT P10636 2/20 0.56
KMT2A Q03164 2/20 0.56
NPC1 O15118 1/20 0.56
CYP1A2 P05177 1/20 0.56
POLB P06746 1/20 0.56
RAB9A P51151 1/20 0.56
ATM Q13315 1/20 0.56
PDIA6 Q15084 1/20 0.53
PDE10A Q9Y233 1/20 0.50
TSHR P16473 2/20 0.45
CASP1 P29466 2/20 0.45
CA2 P00918 5/20 0.43
CA12 O43570 3/20 0.43
CA1 P00915 3/20 0.43
CA4 P22748 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6191775 0.98 L3MBTL1 (0.68) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL4363463 0.84 L3MBTL1 (0.73) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL30431668 0.83 L3MBTL1 (1.00) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL31452114 0.83 L3MBTL1 (0.53) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL342932 0.83 L3MBTL1 (0.53) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL2544336 0.83 L3MBTL1 (1.00) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL11332582 0.81 HTR6 (0.55) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL11334860 0.81 L3MBTL1 (0.49) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL31618978 0.81 L3MBTL1 (0.68) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1
SCHEMBL158650 0.81 L3MBTL1 (0.68) L3MBTL1ALDH1A1KDM4ECYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1901747-A2 PYRIMIDINE-BASED CDK INHIBITORS FOR TREATING PAIN Ingenium Pharmaceuticals AG (DE) 2008-03-26 EP claimed
WO-2006125616-A2 PYRIMIDINE-BASED CDK INHIBITORS FOR TREATING PAIN INGENIUM PHARMACEUTICALS AG (DE) 2006-11-30 WO claimed
EP-1089763-B1 AGENTS FOR SPECIFICALLY INHIBITING OSTEOCLASTIC BONE RESORPTION DIETSCH PETER (DE) 2002-09-25 EP claimed
EP-0779906-B1 EPOXY RESIN MIXTURES FOR PREPREGS AND COMPOSITES SIEMENS AG (DE) 1998-07-08 EP claimed
US-5759690-A PHOSPHORUS MODIFIED, FIRE RETARDANT, CIRCUIT BOARDS SIEMENS AKTIENGESELLSCHAFT (DE) 1998-06-02 US claimed
EP-0779906-A1 EPOXY RESIN MIXTURES FOR PREPREGS AND COMPOSITES SIEMENS AKTIENGESELLSCHAFT (DE) 1997-06-25 EP claimed
WO-1996007686-A1 EPOXY RESIN MIXTURES FOR PREPREGS AND COMPOSITES SIEMENS AKTIENGESELLSCHAFT (DE) 1996-03-14 WO claimed
CN-113631548-B Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2023-06-06 CN disclosed
CN-113631548-A Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2021-11-09 CN disclosed
US-10179124-B2 Benzamides and related inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2019-01-15 US disclosed
US-20180036296-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA COR THERAPEUTICS, INC. 2018-02-08 US disclosed
CN-105647221-B Method for preparing C.I. pigment red 185 上虞市新利化工有限公司 2017-05-10 CN disclosed
US-9629831-B2 Benzamides and related inhibitors of factor XA MILLENNIUM PHARMACEUTICALS, INC. (US) 2017-04-25 US disclosed
EP-0779906-B1 EPOXY RESIN MIXTURES FOR PREPREGS AND COMPOSITES SIEMENS AG (DE) 1998-07-08 EP disclosed
US-5759690-A PHOSPHORUS MODIFIED, FIRE RETARDANT, CIRCUIT BOARDS SIEMENS AKTIENGESELLSCHAFT (DE) 1998-06-02 US disclosed
EP-0779906-A1 EPOXY RESIN MIXTURES FOR PREPREGS AND COMPOSITES SIEMENS AKTIENGESELLSCHAFT (DE) 1997-06-25 EP disclosed
WO-1996007686-A1 EPOXY RESIN MIXTURES FOR PREPREGS AND COMPOSITES SIEMENS AKTIENGESELLSCHAFT (DE) 1996-03-14 WO disclosed
US-4618526-A Curable compositions containing multiglycidyl ethers and a sulfonic acid amide THE DOW CHEMICAL COMPANY (US) 1986-10-21 US disclosed
US-3991188-A SALURETICS BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-11-09 US disclosed
US-3977996-A CHROMIUM (III) CARBOXYLATE, COCATALYST AEROJET-GENERAL CORPORATION (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180036296-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA TFPI, F12, TFPI2 L3MBTL1 1004/4885ALDH1A1 2339/4885KDM4E 1933/4885
US-10179124-B2 Benzamides and related inhibitors of factor Xa TFPI, F12, TFPI2 L3MBTL1 1004/4885ALDH1A1 2339/4885KDM4E 1933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.