Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15186887 | 1.00 | MAPT (0.38) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10359923 | 0.85 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19063793 | 0.80 | NR1H2 (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19098260 | 0.80 | NR1H2 (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19063838 | 0.80 | NR1H2 (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5510114 | 0.80 | NR1H2 (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10841947 | 0.79 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23421852 | 0.78 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL18092280 | 0.77 | GAA (0.49) | MAPTALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL17028515 | 0.76 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264968-A1 | MODIFIED iRNA AGENTS | ALNYLAM PHARMACEUTICALS, INC. | 2016-09-15 | — | — | US | disclosed |