SCHEMBL1807220

SCHEMBL1807220

NCCCCc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.53
CA1 P00915 4/20 0.50
CA12 O43570 3/20 0.50
CA9 Q16790 3/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA7 P43166 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
MAOA P21397 1/20 0.50
F2 P00734 2/20 0.48
TMPRSS4 Q9NRS4 2/20 0.48
TSHR P16473 2/20 0.48
TP53 P04637 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
ALDH1A1 P00352 1/20 0.47
NT5E P21589 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9390746 0.98 CA2 (0.51) CA2CA1CA12CA9CA4
Hydrochloric Acid SCHEMBL28969287 0.98 CA2 (0.51) CA2CA1CA12CA9CA4
SCHEMBL28596556 0.98 CA2 (0.54) CA2CA1CA12CA9CA4
SCHEMBL9387354 0.96 CA2 (0.53) CA2CA1CA12CA9CA4
SCHEMBL9391245 0.96 CA2 (0.53) CA2CA1CA12CA9CA4
SCHEMBL9387246 0.96 CA2 (0.53) CA2CA1CA12CA9CA4
SCHEMBL9391279 0.96 CA2 (0.53) CA2CA1CA12CA9CA4
SCHEMBL9388355 0.96 CA2 (0.53) CA2CA1CA12CA9CA4
SCHEMBL9390767 0.96 CA2 (0.53) CA2CA1CA12CA9CA4
SCHEMBL9388371 0.96 CA2 (0.53) CA2CA1CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667230-A Triazines with thiosulfonate end groups and process for their preparation 弗雷克斯系统美国公司 2023-01-31 CN disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed
US-5498605-A ANTIISCHEMIC AGENTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-03-12 US disclosed
WO-1994002497-A1 SULFO-DERIVATIVES OF ADENOSINE THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CA2 1279/4885CA1 798/4885CA12 1243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.