Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 9/20 | 1.00 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL18049866 | 0.87 | NUDT1 (0.76) | NUDT1MAPK8 | |
| SCHEMBL20219465 | 0.75 | L3MBTL1 (0.61) | NUDT1L3MBTL1 | |
| SCHEMBL23472166 | 0.74 | NUDT1 (0.59) | NUDT1L3MBTL1 | |
| SCHEMBL2745753 | 0.74 | NUDT1 (0.58) | NUDT1GRM4 | |
| SCHEMBL14230821 | 0.74 | NUDT1 (0.58) | NUDT1L3MBTL1GRM4 | |
| SCHEMBL17024304 | 0.73 | NUDT1 (0.57) | NUDT1 | |
| SCHEMBL18049860 | 0.71 | NUDT1 (0.56) | NUDT1IDH1 | |
| SCHEMBL9925937 | 0.71 | NUDT1 (0.55) | NUDT1GRM4 | |
| SCHEMBL9885018 | 0.71 | NUDT1 (0.55) | NUDT1L3MBTL1GRM4 | |
| SCHEMBL9884961 | 0.71 | NUDT1 (0.55) | NUDT1L3MBTL1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016145383-A1 | MTH1 INHIBITORS FOR TREATING DISEASE | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2016-09-15 | — | — | WO | disclosed |