SCHEMBL1807480

SCHEMBL1807480

NC(=O)c1cc(O)cc(C(N)=O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 6/20 0.58
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA5A P35218 1/20 0.48
CYP3A4 P08684 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
FASN P49327 1/20 0.44
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441865 0.94 PARP1 (0.58) PARP1CA12CA1CA2CA7
Hydrochloric Acid SCHEMBL31548602 0.92 PARP1 (0.56) PARP1CA12CA1CA2CA7
SCHEMBL1804171 0.90 CA12 (0.68) PARP1CA12CA1CA2CA7
SCHEMBL813450 0.87 PARP1 (0.53) PARP1CA1CA2CYP3A4SMN1; SMN2
SCHEMBL6093793 0.85 PARP1 (0.50) PARP1CA12CA1CA2CA7
SCHEMBL25159913 0.83 PARP1 (0.52) PARP1CA12CA1CA2CA7
SCHEMBL13917960 0.83 HCAR1 (0.65) PARP1CA12CA1CA2CA7
Resorcinol SCHEMBL8376233 0.83 PARP1 (0.79) PARP1CA12CA1CA2CA7
Butane SCHEMBL6001783 0.83 CA12 (0.50) PARP1CA12CA1CA2CA7
SCHEMBL4339312 0.83 HCAR1 (0.65) PARP1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479101-B Supramolecular gel composition 中北大学 2023-01-17 CN claimed
CN-114479101-A Supramolecular gel composition 中北大学 2022-05-13 CN claimed
JP-2270848-A None JP disclosed
CN-114008065-B Glycyrrhetinic acid derivatives for the treatment of hyperkalemia 阿德利克斯股份有限公司 2025-03-11 CN disclosed
CN-114479101-B Supramolecular gel composition 中北大学 2023-01-17 CN disclosed
CN-114479101-A Supramolecular gel composition 中北大学 2022-05-13 CN disclosed
CN-114008065-A Glycyrrhetinic acid derivatives for treating hyperkalemia 阿德利克斯股份有限公司 2022-02-01 CN disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed
US-7695525-B2 Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof THE PROCTER & GAMBLE COMPANY (US) 2010-04-13 US disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
JP-H02270848-A NOVEL DIAMINE COMPOUND AND PRODUCTION THEREOF TOMOEGAWA PAPER CO LTD 1990-11-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 PARP1 4411/4885CA12 1243/4885CA1 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.