Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.43 |
| ▸ | PYGB | P11216 | 1/20 | 0.42 |
| ▸ | CD69 | Q07108 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877144 | 0.90 | KDM4E (0.64) | KDM4ELMNACYP2D6CYP2C19CA2 | |
| SCHEMBL11881610 | 0.90 | KDM4E (0.64) | KDM4ELMNACYP2D6CYP2C19CA2 | |
| SCHEMBL11877137 | 0.90 | KDM4E (0.64) | KDM4ELMNACYP2D6CYP2C19CA2 | |
| SCHEMBL11877654 | 0.90 | KDM4E (0.64) | KDM4ELMNACYP2D6CYP2C19CA2 | |
| Streptozosin SCHEMBL444089 | 0.84 | LMNA (1.00) | KDM4ELMNACYP2D6CYP2C19ALDH1A1 | |
| Streptozosin SCHEMBL10262780 | 0.84 | LMNA (1.00) | KDM4ELMNACYP2D6CYP2C19ALDH1A1 | |
| Streptozosin SCHEMBL2351420 | 0.84 | LMNA (1.00) | KDM4ELMNACYP2D6CYP2C19ALDH1A1 | |
| Streptozosin SCHEMBL444088 | 0.84 | LMNA (1.00) | KDM4ELMNACYP2D6CYP2C19ALDH1A1 | |
| Streptozosin SCHEMBL18402590 | 0.84 | LMNA (1.00) | KDM4ELMNACYP2D6CYP2C19ALDH1A1 | |
| Streptozosin SCHEMBL13840968 | 0.84 | LMNA (1.00) | KDM4ELMNACYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016142508-A1 | COMPOSITION FOR TREATING PANCREATIC NEUROENDOCRINE TUMOURS | Centre Léon-Bérard (FR) | 2016-09-15 | — | — | WO | disclosed |