Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | LGALS8 | O00214 | 8/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 5/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | PYGB | P11216 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877654 | 1.00 | KDM4E (0.64) | KDM4ELMNACYP2D6CYP2C19LGALS8 | |
| SCHEMBL11881610 | 1.00 | KDM4E (0.64) | KDM4ELMNACYP2D6CYP2C19LGALS8 | |
| SCHEMBL11877144 | 1.00 | KDM4E (0.64) | KDM4ELMNACYP2D6CYP2C19LGALS8 | |
| SCHEMBL18075995 | 0.90 | KDM4E (0.72) | KDM4ELMNACYP2D6CYP2C19LGALS8 | |
| SCHEMBL11777332 | 0.79 | ALDH1A1 (0.56) | LGALS8LGALS3LGALS7; LGALS7BLGALS1PYGB | |
| SCHEMBL19392067 | 0.79 | ALDH1A1 (0.56) | LGALS8LGALS3LGALS7; LGALS7BLGALS1PYGB | |
| SCHEMBL11777325 | 0.79 | ALDH1A1 (0.56) | LGALS8LGALS3LGALS7; LGALS7BLGALS1PYGB | |
| SCHEMBL19309367 | 0.79 | ALDH1A1 (0.56) | LGALS8LGALS3LGALS7; LGALS7BLGALS1PYGB | |
| Streptozosin SCHEMBL444088 | 0.79 | LMNA (1.00) | KDM4ELMNACYP2D6CYP2C19PYGB | |
| Streptozosin SCHEMBL2351420 | 0.79 | LMNA (1.00) | KDM4ELMNACYP2D6CYP2C19PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940383-A | ANTICANCER | STANFORD RESEARCH INSTITUTE (US) | 1976-02-24 | — | — | US | disclosed |