Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16584901 | 0.94 | ALDH1A1 (0.39) | PIK3CDHRH3POLB | |
| SCHEMBL18076637 | 0.88 | PIK3CD (0.42) | PIK3CDHRH3JAK1POLBTP53 | |
| SCHEMBL16584926 | 0.87 | PIK3CD (0.40) | PIK3CDHRH3POLBTP53PIK3CG | |
| SCHEMBL21178476 | 0.84 | POLB (0.38) | PIK3CDJAK1POLBTP53PIK3CA | |
| SCHEMBL18076653 | 0.83 | POLB (0.53) | POLBTP53MAPTGAA | |
| SCHEMBL21178215 | 0.83 | PIK3CD (0.37) | PIK3CDJAK1POLBTP53PIK3CA | |
| SCHEMBL21178453 | 0.82 | PIK3CD (0.45) | PIK3CDJAK1POLBTP53PIK3CA | |
| SCHEMBL16584875 | 0.82 | SMN1; SMN2 (0.41) | PIK3CDHRH3POLBTP53MAPT | |
| SCHEMBL16597162 | 0.82 | HSP90AB1 (0.49) | PIK3CDMAPT | |
| SCHEMBL16584903 | 0.81 | ALDH1A1 (0.39) | PIK3CDHRH3PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016149160-A1 | SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-09-22 | — | — | WO | disclosed |