Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15630881 | 0.87 | HRH3 (0.53) | HRH3PROKR1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL3742386 | 0.86 | PIK3CA (0.56) | PROKR1KDM4EALDH1A1ADRA1ARECQL | |
| SCHEMBL3750019 | 0.83 | HRH3 (0.57) | HRH3PROKR1KDM4EALDH1A1RAB9A | |
| SCHEMBL15630937 | 0.81 | RAB9A (0.63) | HRH3KDM4EALDH1A1ADRA1ARAB9A | |
| SCHEMBL18080824 | 0.80 | MAP4K4 (0.55) | HRH3 | |
| SCHEMBL19202594 | 0.79 | PROKR1 (0.53) | HRH3PROKR1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL30378524 | 0.79 | PROKR1 (0.53) | HRH3PROKR1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL26089568 | 0.78 | HRH3 (0.51) | HRH3PROKR1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL15630696 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15630932 | 0.77 | ALDH1A1 (0.54) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447090-B2 | Imidazopyridine compounds | ASTELLAS PHARMA INC. (JP) | 2016-09-20 | — | — | US | disclosed |