SCHEMBL18079755

SCHEMBL18079755

C#CSc1cc(SC#N)c(N)nc1N

nearest known ligand 0.84

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.84
USP8 P40818 1/20 0.84
USP5 P45974 1/20 0.84
USP4 Q13107 1/20 0.84
USP7 Q93009 1/20 0.84
MYC P01106 2/20 0.32
WDR5 P61964 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13024499 0.92 USP2 (1.00) USP2USP8USP5USP4USP7
SCHEMBL13065926 0.84 USP2 (0.84) USP2USP8USP5USP4USP7
SCHEMBL13985248 0.78 USP2 (0.74) USP2USP8USP5USP4USP7
SCHEMBL10412909 0.69 USP2 (0.60) USP2USP8USP5USP4USP7
SCHEMBL11173991 0.66 USP2 (0.56) USP2USP8USP5USP4USP7
SCHEMBL9387702 0.64 USP2 (0.53) USP2USP8USP5USP4USP7
SCHEMBL10413718 0.61 USP2 (0.50) USP2USP8USP5USP4USP7
SCHEMBL11367939 0.58 USP2 (0.47) USP2USP8USP5USP4USP7
SCHEMBL11373307 0.58 USP2 (0.47) USP2USP8USP5USP4USP7
SCHEMBL11373902 0.58 USP2 (0.47) USP2USP8USP5USP4USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160264933-A1 CELL DIFFERENTIATION MARKER AND ITS USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS) 2016-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264933-A1 CELL DIFFERENTIATION MARKER AND ITS USES MYADM, USP3, USP2 USP2 3/4885USP8 22/4885USP5 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.