USP3

Ubiquitin carboxyl-terminal hydrolase 3 · Q9Y6I4 · USP3 on Sugi Atlas →

65 patent compounds predicted against USP3, 36 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL15817526 SCHEMBL15817526 0.45 2/20
SCHEMBL11563775 SCHEMBL11563775 0.44 2/20
SCHEMBL15817525 SCHEMBL15817525 0.39 2/20
SCHEMBL24814139 SCHEMBL24814139 0.67 1/20
SCHEMBL24814111 SCHEMBL24814111 0.56 1/20
SCHEMBL28733374 SCHEMBL28733374 0.54 1/20
SCHEMBL24814112 SCHEMBL24814112 0.52 1/20
SCHEMBL5746178 SCHEMBL5746178 0.48 1/20
SCHEMBL29505151 SCHEMBL29505151 0.48 1/20
SCHEMBL6353135 SCHEMBL6353135 0.48 1/20
SCHEMBL23888889 SCHEMBL23888889 0.48 1/20
SCHEMBL24025427 SCHEMBL24025427 0.47 1/20
SCHEMBL14112381 SCHEMBL14112381 0.47 1/20
SCHEMBL5750800 SCHEMBL5750800 0.46 1/20
SCHEMBL31638576 SCHEMBL31638576 0.46 1/20
SCHEMBL4945778 SCHEMBL4945778 0.46 1/20
SCHEMBL24025429 SCHEMBL24025429 0.46 1/20
SCHEMBL18547109 SCHEMBL18547109 0.45 1/20
SCHEMBL3070912 SCHEMBL3070912 0.45 1/20
SCHEMBL4945586 SCHEMBL4945586 0.45 1/20

Clinical trials — most relevant to USP3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study to Evaluate the Safety, Immunogenicity, and Efficacy of UB-612 COVID-19 Vaccine PHASE2/PHASE3WITHDRAWN
Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Diet and Exercise Alone(UNIGUIDE-1) PHASE3NOT_YET_RECRUITING
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes PHASE2UNKNOWN
Relapsed and/or Refractory Non-Hodgkin Lymphoma Study PHASE2WITHDRAWN
A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma PHASE2WITHDRAWN
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma PHASE2SUSPENDED
The Effect of Roxadustat on Renal Oxygenation in Diabetes Nephropathy PHASE2NOT_YET_RECRUITING
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
A Phase 1 Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-313 in Healthy Participants PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome nanRECRUITING
Clinical Trial of Levodopa/Carbidopa ( Sinemet) Therapy in Angel Man Syndrome nanCOMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure nanCOMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 nanRECRUITING
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin nanUNKNOWN
Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma nanCOMPLETED
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit nanCOMPLETED
Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer's Disease nanCOMPLETED
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS nanCOMPLETED
ADAPT: Efficacy of a Dietary Supplement During and After Exercise nanCOMPLETED
Genetic Studies of Inflammatory Bowel Disease nanCOMPLETED
Using Mobile Technology to Improve Self-Regulation nanCOMPLETED
Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin Carboxy-terminal Hydrolase L1 (UCH-L1) to Exclude Lesions Linked to Significant Traumatic Brain Injuries nanRECRUITING
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome nanRECRUITING
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a USP3 binder may also engage these)

ProteinNameSimilarity
Q91W36 0.999 Q91W36 →
Q6DCJ1 0.975 Q6DCJ1 →
Q6GNI6 0.973 Q6GNI6 →
Q9H0E7 0.970 Q9H0E7 →
D2HBJ8 0.969 D2HBJ8 →
Q5DU02 0.969 Q5DU02 →
A6H8I0 0.967 A6H8I0 →
Q5XGZ2 0.966 Q5XGZ2 →
Q6NTR6 0.964 Q6NTR6 →
Q0V9G5 0.964 Q0V9G5 →
P0C8Z3 0.963 P0C8Z3 →
A0JM59 0.962 A0JM59 →
Q7ZUM8 0.962 Q7ZUM8 →
P34547 0.961 P34547 →
Q9UPT9 0.961 Q9UPT9 →
A5PN09 0.961 A5PN09 →
Q8C2S0 0.960 Q8C2S0 →
USP20 Ubiquitin carboxyl-terminal hydrolase 20 0.960 landscape →
Q70EL2 0.960 Q70EL2 →
Q28CN3 0.960 Q28CN3 →
Q8R5K2 0.959 Q8R5K2 →
Q8LAM0 0.959 Q8LAM0 →
A6NNY8 0.958 A6NNY8 →
A7Z056 0.958 A7Z056 →
Q8K387 0.957 Q8K387 →
Q9VVR1 0.957 Q9VVR1 →
Q6P9L4 0.956 Q6P9L4 →
Q70CQ1 0.956 Q70CQ1 →
Q8CEG8 0.955 Q8CEG8 →
B1WBD7 0.955 B1WBD7 →