Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 4/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631381 | 1.00 | KDM4E (0.41) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL16631386 | 0.89 | KDM4E (0.42) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL16631315 | 0.89 | KDM4E (0.40) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL18080205 | 0.89 | KDM4E (0.42) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL18080191 | 0.89 | KDM4E (0.40) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL16631892 | 0.87 | KDM4E (0.39) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL18080224 | 0.87 | KDM4E (0.39) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL16631383 | 0.86 | KDM4E (0.41) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL18080195 | 0.86 | KDM4E (0.41) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL16631258 | 0.84 | TSHR (0.33) | LMNAMAPTPMP22SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | KDM4E 4689/4885GMNN 556/4885LMNA 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.