Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631529 | 0.90 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL18081963 | 0.85 | — | — | |
| SCHEMBL18081845 | 0.84 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL16631582 | 0.82 | KDM4E (0.30) | KDM4EALDH1A1 | |
| SCHEMBL18081977 | 0.81 | KDM4E (0.31) | KDM4EALDH1A1 | |
| SCHEMBL18081915 | 0.81 | PDE3B (0.31) | — | |
| SCHEMBL16631772 | 0.81 | KMT2A (0.32) | KDM4EALDH1A1 | |
| SCHEMBL18081944 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1 | |
| SCHEMBL18081947 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL18081828 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | KDM4E 4689/4885ALDH1A1 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.