⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081789 | 0.88 | — | — | |
| SCHEMBL16631761 | 0.87 | — | — | |
| SCHEMBL18081980 | 0.85 | KDM4E (0.31) | — | |
| SCHEMBL18081817 | 0.85 | KDM4E (0.31) | — | |
| SCHEMBL18081824 | 0.82 | — | — | |
| SCHEMBL16631759 | 0.82 | KMT2A (0.32) | — | |
| SCHEMBL18080582 | 0.82 | — | — | |
| SCHEMBL18081850 | 0.82 | — | — | |
| SCHEMBL16631530 | 0.80 | — | — | |
| SCHEMBL18081488 | 0.79 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |