Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631772 | 0.86 | KMT2A (0.32) | KMT2AMEN1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL16631362 | 0.84 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL18081963 | 0.82 | — | — | |
| SCHEMBL18080582 | 0.78 | — | — | |
| SCHEMBL16631764 | 0.77 | LMNA (0.33) | KMT2AMEN1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL16631765 | 0.77 | NPSR1 (0.33) | ALDH1A1NPSR1RXFP1 | |
| SCHEMBL16631754 | 0.75 | MEN1 (0.33) | KMT2AMEN1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL16631758 | 0.73 | LMNA (0.30) | LMNA | |
| SCHEMBL18081817 | 0.73 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL16631774 | 0.71 | MEN1 (0.33) | KMT2AMEN1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |