SCHEMBL1808228

SCHEMBL1808228

OC#Cc1ccccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
CA2 P00918 5/20 0.45
HPGD P15428 4/20 0.45
ALOX15 P16050 3/20 0.45
LMNA P02545 3/20 0.45
HSD17B10 Q99714 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
KDM4E B2RXH2 3/20 0.45
CA4 P22748 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
EGFR P00533 2/20 0.45
FYN P06241 2/20 0.45
MMP9 P14780 2/20 0.45
RECQL P46063 2/20 0.45
NPC1 O15118 2/20 0.45
MAPT P10636 2/20 0.45
CA12 O43570 2/20 0.45
CA14 Q9ULX7 2/20 0.45
GMNN O75496 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15688668 0.86 ALDH1A1 (0.53) ALDH1A1CA2HPGDALOX15LMNA
SCHEMBL5312824 0.81 ALDH1A1 (0.47) ALDH1A1CA2HPGDALOX15LMNA
SCHEMBL7599064 0.78
SCHEMBL25190694 0.77 FFAR1 (0.43) ALDH1A1CA2HPGDALOX15LMNA
SCHEMBL18286553 0.77 ALDH1A1 (0.43) ALDH1A1CA2HPGDALOX15LMNA
SCHEMBL17288705 0.77 ALDH1A1 (0.43) ALDH1A1CA2HPGDALOX15LMNA
SCHEMBL2045121 0.77 ALDH1A1 (0.43) ALDH1A1CA2HPGDALOX15LMNA
SCHEMBL673209 0.75 FFAR1 (0.59) ALDH1A1CA2HPGDALOX15LMNA
SCHEMBL17443017 0.75 ALDH1A1 (0.53) ALDH1A1CA2HPGDALOX15LMNA
SCHEMBL10442103 0.73 FFAR1 (0.41) ALDH1A1CA2HPGDALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586303-B Recyclable flame-retardant thermosetting resin based on carbonyl alkyne-alcohol click reaction, and preparation method and application thereof 江西科技师范大学 2024-07-09 CN disclosed
CN-117586303-A Recyclable flame-retardant thermosetting resin based on carbonyl alkyne-alcohol click reaction, and preparation method and application thereof 江西科技师范大学 2024-02-23 CN disclosed
CN-113004663-A Low-dielectric alloy material and preparation method and application thereof 桂林理工大学 2021-06-22 CN disclosed
CN-112940458-A Low dielectric liquid crystal composite material and preparation method and application thereof 桂林理工大学 2021-06-11 CN disclosed
US-7943722-B2 Fire-retardant polyarylate resin containing dihydroxyphenylacetylene and compositions thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2011-05-17 US disclosed
US-6881811-B2 Improved heat resistance and low relative permittivity; insulating films for electronic devices/multilayerd wiring boards ASAHI GLASS COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20040147710-A1 Improved heat resistance and low relative permittivity; insulating films for electronic devices/multilayerd wiring boards ASAHI GLASS COMPANY LIMITED (JP) 2004-07-29 US disclosed