SCHEMBL17288705

SCHEMBL17288705

Oc1ccccc1C#CF

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
ALOX15 P16050 3/20 0.43
CA2 P00918 3/20 0.43
LMNA P02545 3/20 0.43
HPGD P15428 3/20 0.43
HSD17B10 Q99714 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 2/20 0.43
EGFR P00533 2/20 0.43
FYN P06241 2/20 0.43
MAPT P10636 2/20 0.43
MMP9 P14780 2/20 0.43
CA4 P22748 2/20 0.43
RECQL P46063 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NFKB1 P19838 2/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15688668 0.84 ALDH1A1 (0.53) ALDH1A1ALOX15CA2LMNAHPGD
SCHEMBL4579718 0.81 APP (0.35) ALDH1A1HPGDHSD17B10KDM4ENPC1
SCHEMBL5312824 0.79 ALDH1A1 (0.47) ALDH1A1ALOX15CA2LMNAHPGD
SCHEMBL1808228 0.77 ALDH1A1 (0.45) ALDH1A1ALOX15CA2LMNAHPGD
SCHEMBL25190694 0.75 FFAR1 (0.43) ALDH1A1ALOX15CA2LMNAHPGD
SCHEMBL18286553 0.75 ALDH1A1 (0.43) ALDH1A1ALOX15CA2LMNAHPGD
SCHEMBL2045121 0.75 ALDH1A1 (0.43) ALDH1A1ALOX15CA2LMNAHPGD
SCHEMBL673209 0.73 FFAR1 (0.59) ALDH1A1ALOX15CA2LMNAHPGD
SCHEMBL17443017 0.73 ALDH1A1 (0.53) ALDH1A1ALOX15CA2LMNAHPGD
SCHEMBL16457122 0.72 GRM5 (0.43) IDO1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 ALDH1A1 3053/4885ALOX15 2577/4885CA2 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.