Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | FPR2 | P25090 | 6/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903131 | 0.90 | FPR2 (0.54) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL14902603 | 0.88 | FPR2 (0.74) | CA1CA2FPR2ANPEPTP53 | |
| SCHEMBL14948918 | 0.88 | FPR2 (0.74) | CA1CA2FPR2ANPEPTP53 | |
| SCHEMBL28348560 | 0.83 | FPR2 (0.52) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL16738187 | 0.83 | FPR2 (0.52) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL20484374 | 0.82 | FPR2 (0.56) | FPR2ANPEP | |
| SCHEMBL14889891 | 0.82 | FPR2 (0.56) | FPR2ANPEP | |
| SCHEMBL14902681 | 0.81 | FPR2 (0.53) | FPR2ANPEP | |
| SCHEMBL20484126 | 0.81 | FPR2 (0.53) | FPR2ANPEP | |
| SCHEMBL16588674 | 0.80 | FPR2 (0.57) | FPR2ANPEPTP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776389-B1 | ARYL UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2016-09-21 | — | — | EP | disclosed |