SCHEMBL20484374

SCHEMBL20484374

CC(C)CC(NC(=O)Nc1ccc(SC(F)(F)F)cc1)C(=O)NCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 15/20 0.56
ANPEP P15144 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14889891 1.00 FPR2 (0.56) FPR2ANPEP
SCHEMBL20484126 0.88 FPR2 (0.53) FPR2ANPEP
SCHEMBL14902681 0.88 FPR2 (0.53) FPR2ANPEP
SCHEMBL20484372 0.86 FPR2 (0.75) FPR2ANPEP
SCHEMBL14889715 0.86 FPR2 (0.75) FPR2ANPEP
SCHEMBL14902603 0.86 FPR2 (0.74) FPR2ANPEP
SCHEMBL14948918 0.86 FPR2 (0.74) FPR2ANPEP
SCHEMBL22150336 0.85 FPR2 (0.72) FPR2ANPEP
SCHEMBL14889809 0.85 FPR2 (0.72) FPR2ANPEP
SCHEMBL16588674 0.83 FPR2 (0.57) FPR2ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3078656-B1 AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2020-07-01 EP claimed
CN-106518742-B Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators 阿勒根公司 2020-01-21 CN disclosed
EP-2770989-B1 AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2018-09-05 EP disclosed