Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.43 |
| ▸ | LOX | P28300 | 3/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | UTRN | P46939 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16453525 | 0.84 | NOS3 (0.48) | NOS3NOS1NOS2LOXL2LOX | |
| SCHEMBL17000198 | 0.83 | LOXL2 (0.41) | LOXL2LOXHCRTR1HCRTR2UTRN | |
| SCHEMBL4536253 | 0.82 | HCRTR1 (0.40) | LOXL2LOXHCRTR1HCRTR2UTRN | |
| SCHEMBL30329140 | 0.82 | RECQL (0.47) | LOXL2LOXHCRTR1HCRTR2UTRN | |
| SCHEMBL13164105 | 0.82 | LOXL2 (0.61) | LOXL2LOXHCRTR1HCRTR2 | |
| SCHEMBL1437199 | 0.82 | RECQL (0.47) | LOXL2LOXHCRTR1HCRTR2UTRN | |
| SCHEMBL14925194 | 0.82 | HCRTR1 (0.40) | LOXL2LOXHCRTR1HCRTR2UTRN | |
| SCHEMBL21776375 | 0.81 | NOS3 (0.46) | NOS3NOS1NOS2LOXL2LOX | |
| Hydrochloric Acid SCHEMBL25210344 | 0.81 | LOXL2 (0.59) | LOXL2LOXHCRTR1HCRTR2 | |
| SCHEMBL31018746 | 0.79 | LOXL2 (0.45) | LOXL2LOXHCRTR1HCRTR2UTRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900660-B1 | HERBICIDAL AND FUNGICIDAL 3-HETEROARYLISOXAZOLIN-5-CARBOXAMIDES AND 3-HETEROARYLISOXAZOLIN-5-THIOAMIDES | BAYER CROPSCIENCE AG (DE) | 2018-01-17 | — | — | EP | disclosed |
| EP-2900644-B1 | HERBICIDAL AND FUNGICIDAL 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLIN-5-CARBOXAMIDES AND 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLIN-5-THIOAMIDES | BAYER CROPSCIENCE AG (DE) | 2016-09-21 | — | — | EP | disclosed |