Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701128 | 0.90 | KDM4E (0.53) | KDM4EHSD17B10TSHRPKMALDH1A1 | |
| SCHEMBL18083272 | 0.88 | IDO1 (0.52) | KDM4EHSD17B10TSHRPKMALDH1A1 | |
| SCHEMBL9522612 | 0.88 | KDM4E (0.51) | KDM4EHSD17B10TSHRPKMALDH1A1 | |
| SCHEMBL18083273 | 0.88 | KDM4E (0.51) | KDM4EHSD17B10TSHRPKMALDH1A1 | |
| SCHEMBL18701131 | 0.85 | KDM4E (0.52) | KDM4EHSD17B10TSHRPKMALDH1A1 | |
| SCHEMBL18059954 | 0.84 | ADORA3 (0.55) | KDM4EHSD17B10TSHRALDH1A1L3MBTL1 | |
| SCHEMBL9263585 | 0.82 | KDM4E (0.49) | KDM4EHSD17B10TSHRPKMALDH1A1 | |
| SCHEMBL9263582 | 0.82 | KDM4E (0.49) | KDM4EHSD17B10TSHRPKMALDH1A1 | |
| SCHEMBL18701262 | 0.81 | KDM4E (0.51) | KDM4EHSD17B10TSHRPKMALDH1A1 | |
| SCHEMBL2776006 | 0.76 | KDM4E (0.62) | KDM4EHSD17B10TSHRPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170098783-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2017-04-06 | — | — | US | disclosed |
| US-20170098783-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2017-04-06 | — | — | US | disclosed |
| EP-3070092-A1 | 3-PHENYL-THIAZOLO[3,2-A]BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT OF CANCER AND FOR THE MANIPULATION OF CULTURED ALDEHYDE DEHYDROGENASE 1 (ALDH-1) POSITIVE CANCER CELLS | King Saud University (SA) | 2016-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098783-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | EED, EML4, MT-ND4L | KDM4E 2196/4885HSD17B10 3823/4885TSHR 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.