Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808343 | 1.00 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA | |
| SCHEMBL1808341 | 1.00 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA | |
| Hydrochloric Acid SCHEMBL1808846 | 0.98 | NPSR1 (0.34) | NPSR1GRM4GRM2GRM3LMNA | |
| Hydrochloric Acid SCHEMBL1154207 | 0.98 | NPSR1 (0.34) | NPSR1GRM4GRM2GRM3LMNA | |
| Hydrochloric Acid SCHEMBL1808844 | 0.98 | NPSR1 (0.34) | NPSR1GRM4GRM2GRM3LMNA | |
| SCHEMBL31415546 | 0.93 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA | |
| SCHEMBL31415504 | 0.93 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA | |
| SCHEMBL31415451 | 0.93 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA | |
| SCHEMBL24511780 | 0.83 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA | |
| SCHEMBL2746669 | 0.83 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081730-A1 | 4-HYDROXY-2-OXO-1,2-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXAMIDE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER | TEON THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-2496556-B1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2018-12-26 | — | — | EP | disclosed |
| US-9018383-B2 | Acylamino-substituted cyclic carboxylic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2015-04-28 | — | — | US | disclosed |
| US-20140088158-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-03-27 | — | — | US | disclosed |
| US-8618304-B2 | Acylamino-substituted cyclic carboxylic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2013-12-31 | — | — | US | disclosed |
| US-20120264790-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-10-18 | — | — | US | disclosed |
| EP-2496556-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011053948-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2011-05-05 | — | — | WO | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-6933261-B2 | 2,4,5-Trisubstituted phenylketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-23 | — | — | US | disclosed |
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | LIEB FOLKER (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6511942-B1 | Animal husbandry, veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-28 | — | — | US | disclosed |
| US-6486343-B1 | Substituted phenyl keto enols as pesticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | disclosed |
| US-6388123-B1 | MITICIDE, INSECTICIDE FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |
| US-20010004629-A1 | Substituted phenyl keto enols as pesticides and herbicides | LIEB VOLKER (DE) | 2001-06-21 | — | — | US | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-6110872-A | 3-(2,4,5-TRISUBSTITUTED PHENYL), 4-HYDROXY,5,5-(CYCLOALKYL OR HETEROCYCLOALKYL)PYRROLIN-2-ONE AND DERIVATIVES; METHOD OF MAKING BY INTRAMOLECULAR CONDENSATION OF SPECIFIED COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264790-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | LPAR2, LIPG, EDF1 | NPSR1 984/4885GRM4 2105/4885GRM2 570/4885 |
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, PDHX | NPSR1 3015/4885GRM4 753/4885GRM2 587/4885 |
| US-20140088158-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | LPAR2, LIPG, EDF1 | NPSR1 984/4885GRM4 2105/4885GRM2 570/4885 |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, HPD | NPSR1 3011/4885GRM4 909/4885GRM2 544/4885 |
| US-20010004629-A1 | Substituted phenyl keto enols as pesticides and herbicides | DDT, CYP4X1, CYP1B1 | NPSR1 2807/4885GRM4 1092/4885GRM2 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.