Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.34 |
| ▸ | ODC1 | P11926 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854826 | 0.79 | ODC1 (0.47) | ODC1KDM4EMAPTTHRBBLM | |
| SCHEMBL148366 | 0.67 | ODC1 (0.54) | ODC1KDM4EMAPTTHRBBLM | |
| SCHEMBL18882997 | 0.65 | — | — | |
| SCHEMBL21663995 | 0.65 | — | — | |
| SCHEMBL16259499 | 0.65 | — | — | |
| SCHEMBL5324175 | 0.65 | MEN1 (0.65) | ODC1KDM4EMAPTTHRBBLM | |
| SCHEMBL20636765 | 0.65 | ODC1 (0.38) | PAOXODC1KDM4EMAPTTHRB | |
| SCHEMBL28792659 | 0.65 | ODC1 (0.38) | PAOXODC1KDM4EMAPTTHRB | |
| SCHEMBL15315407 | 0.65 | PAOX (0.44) | PAOXODC1KDM4EMAPTTHRB | |
| Ethylenediamine SCHEMBL20657069 | 0.64 | PAOX (0.36) | PAOXODC1ALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648724-B1 | HYDROXYLATED AMINOTRIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-09-21 | — | — | EP | disclosed |