SCHEMBL2854826

SCHEMBL2854826

NCC[C@@](N)(CS)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.47
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
THRB P10828 1/20 0.39
KMT2A Q03164 1/20 0.39
ARG1 P05089 10/20 0.38
ARG2 P78540 7/20 0.38
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CPB2 Q96IY4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148366 0.85 ODC1 (0.54) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL31588249 0.82
SCHEMBL691126 0.80
SCHEMBL16222762 0.79 MEN1 (0.47) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL5321451 0.79 MEN1 (0.47) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL18084239 0.79 PAOX (0.34) ODC1THRBKDM4EMAPTBLM
Hydrochloric Acid SCHEMBL2748363 0.78 ARG2 (0.44) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL5324175 0.76 MEN1 (0.65) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL16222760 0.76 ARG2 (0.46) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL4318239 0.76 GGT1 (0.53) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221736-A1 METHOD FOR PREDICTING SUSCEPTIBILITY TO A MENTAL DISORDER FONDATION ALAMAYA (CH) 2010-09-02 US disclosed
US-20090297494-A1 Diagnostic and treatment of a mental disorder CUENOD MICHEL 2009-12-03 US disclosed
US-20060275536-A1 GRAIN PRODUCT WITH INCREASED SOLUBLE FIBER CONTENT AND ASSOCIATED METHODS GENERAL MILLS IP HOLDINGS II, LLC 2006-12-07 US disclosed
US-20060216394-A1 Method and compositions to decrease serum cholesterol levels GENERAL MILLS IP HOLDINGS II, LLC 2006-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297494-A1 Diagnostic and treatment of a mental disorder GSTA1, GSR, GSTM1 ODC1 2789/4885MEN1 4806/4885ALDH1A1 2006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.