SCHEMBL148366

SCHEMBL148366

NCCC(N)(CCN)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.54
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
THRB P10828 1/20 0.44
KMT2A Q03164 1/20 0.44
ARG1 P05089 12/20 0.43
ARG2 P78540 8/20 0.43
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9501854 0.88 ODC1 (0.61) ODC1ARG1ARG2KDM4ELMNA
SCHEMBL2854826 0.85 ODC1 (0.47) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL5324175 0.85 MEN1 (0.65) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL3256585 0.82 ODC1 (0.50) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL29359936 0.79 ODC1 (0.63) ODC1ARG1ARG2KDM4ELMNA
SCHEMBL9450990 0.79 NOS1 (0.44) ODC1MEN1ALDH1A1CYP1A2THRB
SCHEMBL23094070 0.77 ODC1 (0.44) ODC1MEN1CYP1A2KMT2AARG1
SCHEMBL23094075 0.77 ODC1 (0.44) ODC1MEN1CYP1A2KMT2AARG1
SCHEMBL23094069 0.77 ODC1 (0.44) ODC1MEN1CYP1A2KMT2AARG1
SCHEMBL11849715 0.77 ODC1 (0.43) ODC1MEN1ALDH1A1CYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287123-A1 ANTIVIRAL NUCLEOSIDE ANALOGUES VICTORIA LINK LIMITED (NZ) 2024-08-29 US disclosed
EP-4351581-A1 ANTIVIRAL NUCLEOSIDE ANALOGUES Victoria Link Limited (NZ) 2024-04-17 EP disclosed
WO-2022260535-A1 ANTIVIRAL NUCLEOSIDE ANALOGUES VICTORIA LINK LIMITED (NZ) 2022-12-15 WO disclosed
US-8153365-B2 Oligonucleotide analogues EXIQON A/S (DK) 2012-04-10 US disclosed
US-20120058983-A1 Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-03-08 US disclosed
US-8034909-B2 Oligonucleotide analogues EXIQON A/S (DK) 2011-10-11 US disclosed
US-20110245327-A1 Oligonucleotide Analogues EXIQON A/S (DK) 2011-10-06 US disclosed
US-20110237629-A1 AMINO ACID ESTER PRODRUGS AND THE USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-09-29 US disclosed
EP-2341057-A2 Oligonucleotide Analogues Exiqon A/S (DK) 2011-07-06 EP disclosed
US-6376655-B1 APPLYING EXTERNAL STIMULATION; OPTICAL ANISOTROPY RISO NATIONAL LABORATORY (DK) 2002-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287123-A1 ANTIVIRAL NUCLEOSIDE ANALOGUES EBNA1BP2, RPL35, RPL7 ODC1 1964/4885MEN1 3177/4885ALDH1A1 2249/4885
US-20110237629-A1 AMINO ACID ESTER PRODRUGS AND THE USE THEREOF DNPEP, AADAT, DAO ODC1 346/4885MEN1 2336/4885ALDH1A1 1058/4885
US-20110245327-A1 Oligonucleotide Analogues POLRMT, POLM, POLN ODC1 594/4885MEN1 4566/4885ALDH1A1 3811/4885
US-20120058983-A1 Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension ADORA1, ADORA3, ADORA2A ODC1 952/4885MEN1 1018/4885ALDH1A1 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.