Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933968 | 0.78 | — | — | |
| SCHEMBL6454534 | 0.78 | — | — | |
| SCHEMBL6460929 | 0.78 | — | — | |
| SCHEMBL16268178 | 0.75 | CCNE1 (0.33) | — | |
| SCHEMBL17065252 | 0.75 | — | — | |
| SCHEMBL6455262 | 0.74 | CCNE1 (0.36) | — | |
| SCHEMBL6456056 | 0.69 | ALDH1A1 (0.45) | LOXL2 | |
| SCHEMBL16267820 | 0.68 | CCNE1 (0.40) | — | |
| SCHEMBL6127286 | 0.67 | — | — | |
| SCHEMBL13680965 | 0.65 | ERCC5 (0.55) | ERCC5FEN1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499132-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011060000-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |