Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.41 |
| ▸ | S100A10 | P60903 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085047 | 0.97 | DRD1 (0.54) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18085069 | 0.94 | DRD1 (0.50) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18085068 | 0.94 | DRD1 (0.50) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18085070 | 0.94 | DRD1 (0.50) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18064733 | 0.90 | SLC6A2 (0.49) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18064735 | 0.90 | SLC6A2 (0.49) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18085039 | 0.90 | DRD1 (0.48) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18085071 | 0.89 | DRD1 (0.42) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18085055 | 0.84 | DRD1 (0.73) | DRD1KDM4EMTORCYP2D6MAPT | |
| SCHEMBL18085072 | 0.84 | SLC6A2 (0.40) | DRD1KDM4EMTORCYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160272572-A1 | ADENYLYL CYCLASE INHIBITORS FOR NEUROPATHIC AND INFLAMMATORY PAIN | PURDUE RESEARCH FOUNDATION | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272572-A1 | ADENYLYL CYCLASE INHIBITORS FOR NEUROPATHIC AND INFLAMMATORY PAIN | ADCY1, ADCY2, ADCY5 | DRD1 3588/4885KDM4E 3215/4885MTOR 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.